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At higher supplemental doses (500 to 3000 mg daily), niacinamide can cause nausea, liver enzyme elevation, or glucose intolerance, but these effects are unlikely at the low doses used in compounded formulations

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The most important stimuli of prolactin secretion are suckling, stress, pregnancy, and estrogens

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For comparison frameworks, the related GLOW peptide protocol tackles a similar combination question on the dermal-recovery side