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Discussion The global prevalence of obesity is surging at an unprecedented rate, emerging as a major public health crisis and a key driver of metabolic disorders, including T2DM

Per a review published in The New England Journal of Medicine, adults treated with semaglutide therapy lost an average of 14.9% of their body weight after 68 weeks

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These complications are based on animal studies

They identified a specific genetic variant, rs877446, that mimics the effects of GLP-1 receptor agonists by being associated with lower BMI