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72 hours renders it largely inactive

The d-Galactosamine (GalN) and lipopolysaccharide (LPS) treatment that results in hepatic inflammation and subsequent fulminant hepatic failure in mice decreases the liver GSH content which is attenuated by hemin [haem oxygenase-1 (HO-1) inducer], but zinc protoporphyrin [(HO-1) inhibitor] reverses the effects of hemin [59]

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