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Maintaining proper fluid balance is paramount for optimal cellular functioning, and IV administration offers an efficient means to rapidly correct imbalances, particularly when oral intake is not feasible

Besides being a potential source of more reactive free radicals via Fenton reaction, physiological generation of H 2 O 2 fulfills a second messenger role and can be transported across membranes by aquaporins, a family of proteins that act as peroxiporins (Sies, 2014)

Weight-based dosing at 0.2g per kg bodyweight

In spontaneously hypertensive rats, carbidopa, which decreases peripheral dopamine by inhibiting peripheral dopamine synthesis, significantly accelerated the development of hypertension, decreased urinary sodium excretion, and decreased urinary and renal dopamine levels (Yoshimura et al., 1987)

It may increase IGF-1, so monitoring is essential