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Key Distinction: Sterile water = single use, no preservative

This allows the vial to be accessed multiple times under sterile conditions, reducing waste in clinical environments requiring repeated drug reconstitution or administration

Semaglutide is FDA-approved with clinical evidence

Can be combined with Traumeel for anti-inflammatory action

The third cost significance requirement, at 419.66(d)(3), provides that the difference between the estimated average reasonable cost of the devices in the category and the portion of the APC payment amount for the device must exceed 10 percent of the APC payment amount for the related service