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Many patients find it effective not only for controlling diabetes but also for supporting weight loss efforts

Illness during protocol: Acute illness (cold, flu, infection) may temporarily worsen injury symptoms through general inflammation

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There are many factors influencing drug resistance, including overexpression of ABC transporters, drug inactivation, changes in drug targets, apoptotic dysregulation, cancer stem cells and epithelial-to-mesenchymal transitions (Faruk, 2021)

Those with alcohol dependence or excessive recent alcohol consumption were also excluded