This is because you are taking in more nicotine, which can have a sedating effect
doi: 10.1136/tobaccocontrol-2014-052084 Yong H-H, Borland R, Hammond D, et al
This might be a blend we are rescoring or giving a score for the first time
RESULTS Respondent characteristics Most respondents were female, comprising 74.2% (n=239), and were in their third semester, accounting for 41.3% (n=133)
"But we found the e-liquids caused changes in the endothelial cells that are closely related to those seen during the development of cardiovascular disease." The researchers investigated the effect of six different popular e-liquid flavors - fruit, tobacco, sweet tobacco with caramel and vanilla, sweet butterscotch, cinnamon, and menthol - with nicotine levels of 0, 6, and 18 milligrams per milliliter on endothelial cells derived from human iPS cells