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Interestingly, cigarette smoke condensate induced differentiation of THP-1 monocytes into macrophages, resulting in stage-specific activation of the NLRP3 inflammasome and increased IL-1 and IL-18 secretion 52)

And a toothpaste ad from 1915 specifically targets smoking: "Smoke all you want my friend, providing that before you present yourself to me, you wash your mouth with DENTOL" (see fig

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For the jazz musicians and cannabis users of Harlem, leaning into this loaded terminology was a subversive act of wit