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The end product of the pathway is ribose-5-phosphate, utilized for the production of nucleotides, polysaccharides, and coenzymes, and used in RBCs for phosphoribosylpyrophosphate (PRPP) production to generate ADP for use in the EmbdenMeyerhof glycolysis pathway [57,63,64]

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Ferroptosis-related proteins have become attractive targets for many major human diseases that are currently incurable, and some ferroptosis regulators have shown therapeutic effects in clinical trials although further validation of their clinical potential is needed

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