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Several case series (55, 56) and open-label trials (5760) suggest that the combination of a better glycemic control, improved metabolic parameters and bodyweight reductions achieved by exenatide treatment as monotherapy or as add-on to standard therapies may lead to improvements in liver biomarkers and hepatic fat reductions in patients with T2D

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Noninferiority to placebo was established, with a hazard ratio equal to 0.79 (95% CI: 0.57, 1.11) over the median observation time of 16-months