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Two promising medications in this field are cagrilintide and tirzepatide

Paradoxically, fatigue is among the commonly reported adverse effects of GLP-1 therapy, particularly during the initial weeks of treatment or following dose escalation

Al-Aly thinks that might be an underestimate because even though the study followed huge numbers of people, it covered only about four years, so they might have seen more Alzheimers cases if the study had gone on for longer, which might have translated to a larger benefit

doi: 10.1016/j.lfs.2004.08.010

Long-term Digestive Adaptations Over time, the body gets used to not having a gallbladder