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In preclinical cell-based models, hCG is used to interrogate Leydig cell responsiveness, CYP enzyme induction kinetics, and receptor desensitisation and internalisation dynamics
A double-blind, placebo-controlled trial allocated women with active IIH to 12-week dosing of either placebo ( n = 7) or exenatide ( n = 7), a GLP-1R agonist [27]
Plain water without electrolytes also dilutes plasma sodium, suppresses thirst signaling, and increases renal urine output reducing net fluid retention in a way that IV isotonic saline does not
Hartman ML, et al
Approximately 20% may gain over 10% of their body weight [6], further complicating an already challenging clinical and emotional journey
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