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In child injury models, ALC has been shown to improve mitochondrial function, reduce brain swelling, and prevent tissue loss, with continued administration enhancing cerebral energy in healthy mice [41, 45, 46]

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Furthermore, glucagon is a critical regulator of amino acid homeostasis, and amino acids in turn regulate alpha cell function and proliferation [13, 17, 41, 42]

Catalpol effectively alleviates cognitive impairment and neuropathological damage in isoflurane-exposed aged mice, showcasing its neuroprotective effects (Shi et al., 2022)