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However, because glucagon-like peptide-1 receptor agonists work to slow gastric emptying, a safety concern has been raised in patients undergoing deep sedation or general anesthesia regarding gastric aspiration, and considering their long half-life in the blood, they are difficult to manage in the perioperative period

Results Changes in cholesterol content modulate exendin-4-induced GLP-1R behaviours in primary islets and in vivo To determine the effect of increased cholesterol levels on GLP-1R function, we fed mice a standard chow diet supplemented or not with cholesterol for 5 weeks

Indeed it has been hypothesized that depression and vascular disease may be different manifestations of the same genetic substrates 79

In mice with metastatic melanoma, the produced nano complexes subjected to near-infrared (NIR) radiation can provoke potent immune responses and efficiently destroy tumors