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Retatrutide is currently the most powerful weight loss peptide in clinical development, producing 24.2% average weight loss over 48 weeks in Phase 2 trials

integrated TCGA and GEO transcriptomes with machine learning to derive a seven-gene lactylation-related signature (CHERP, DHX9, EMG1, HNRNPH1, LCP1, RPS11, UBE2E1) that stratified patients by survival risk

doi: 10.1046/j.1365-2265.1997.1270942.x