Hygroscopic, Refrigerator, under inert atmosphere solubility DMSO (Slightly), Methanol (Slightly) form Solid pka 9.830.15(Predicted) color White to Off-White Sequence Hexanoyl-Tyr-Ile-Ahx-NH2 InChIKey ADWKPLXLPNPJTR-JTJYXVOQSA-N SMILES C(N)(=O)[C@H]([C@@H](C)CC)N(C(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)CCCCC)CCCCCC(N)=O Description Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met
J Biol Chem 292:1731217323 Laurence A, Pesu M, Silvennoinen O, OShea J (2012) Suppl 2: JAK kinases in health and disease: an update
These modifications are designed to enhance T-cell proliferation and survival, thereby improving clinical outcomes
Zn 2+ , combined with its ionophore pyrithione, has been reported to inhibit the RNA-polymerase activity of coronavirus by inhibiting its replication (47)
In vivo, GPx1 / mice had a deficiency of progenitor cells as they failed to increase progenitor cell number following subcutaneous injection of vascular endothelial growth factor or in response to ischemic injury in the hindlimb ischemia model
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