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Lancet 361(9369):16291641 Strauss MH, Hall AS, Narkiewicz K (2023) The combination of beta-blockers and ACE inhibitors across the spectrum of cardiovascular diseases

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Current trial protocols use once-daily dosing, but the improved bioavailability could theoretically support less frequent administration in the future

Yet vitamin D deficiency is still a widespread problemand numerous studies have linked low blood levels of vitamin D with an increased risk of arterial stiffness and endothelial dysfunction, as well as other cardiovascular issues