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Extensive research has indicated a reduction in glucose oxidation and an enhancement of the Warburg effect and PPP in CRC

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In terms of oxidative stress, levels of malondialdehyde (MDA), 8-iso-prostaglandin F2, and 8-hydroxy-2deoxyguanosine (8-OHdG) were significantly reduced, implying that GLP-1RAs reduce lipid peroxidation and oxidative DNA damage

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