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Sometimes a second agent can be rational

Mauvais-Jarvis F, Manson JE, Stevenson JC, Fonseca VA

Weight Loss: GLP-1 treatment is generally considered for individuals with a BMI over 35, or occasionally at a lower BMI if weight reduction would significantly improve other health conditions, such as hypertension, Type 2 diabetes or increased risk of cardiovascular disease

Additionally, some patients unconsciously increase portion sizes or snacking frequency as medication side effects subside, offsetting the calorie deficit created by reduced hunger

It really is a big quality of life difference, because we are putting so much effort into getting SMI patients to engage more with the real world, Sokolin said