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Retatrutide also reduced pain in patients with knee osteoarthritis, with Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain scores dropping by as much as 4.5 points, a 75.8% reduction with the 9 mg dose, compared with a 2.4 point (40.3%) reduction for placebo

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In the equipotential dosing group, HbA1c was significantly lower at 3 months (HbA1c 7.6%, IQR 6.88.1

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