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During autophagy formation, LC3-I is lipidated under the action of multiple ATGs, converting to LC3-II which binds to the autophagosome membrane [34, 68]
Rather than suppressing the entire immune response, these peptides can potentially shift the balance between pro-inflammatory and anti-inflammatory processes, promote regulatory T cell function, and restore tolerance mechanisms that have broken down in lupus
These physiological responses can accelerate the aging of the skin by breaking down collagen and elastin, leading to the formation of wrinkles and fine lines
Depending on the cause, female infertility may be treatable with surgery or ovulation-inducing medications (eg, clomiphene citrate, letrozole, and gonadotropins)
Nutrients 11 , (2019).
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