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Importantly, both the collapse of m and arrhythmias are blocked by ligands of the mBzR complex, and not by cyclosporine A, the classical permeability transition pore (PTP) inhibitor, indicating a graded redox sensitivity of the target mitochondrial ion channels [6, 7]

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Mutation of SHP2 accounts for more than half of the cases of Noonan syndrome, characterized by proportional short stature, facial dysmorphia, and heart disease (150)

Nanomaterials 6:65 Longmire M, Choyke PL, Kobayashi H (2008) Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats