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A review of the contribution of mast cells in wound healing: involved molecular and cellular mechanisms

Drug Design, Development and Therapy , 9, 2485 2499

Initial clinical trials appeared to validate the beneficial effect of incretins, specifically: A small open-label Phase 1 study (2013) with exenatide (Byetta, twice daily, beginning with 5 g/dose for a month and then increased to 10 g/dose) in 45 patients with PD of moderate severity

In addition, although the domestically developed PD-1 inhibitors toripalimab and tislelizumab were associated with relatively smaller overall numbers of adverse event reports, both agents demonstrated disproportionately high signal strength for immune-mediated lung disease and interstitial lung disease

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