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Most benign lesions are products of inflammation resulting from microbial infestations

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Despite demonstrating efficacy in reversing MASH, maintaining life-style changes over the long term is challenging for most patients, and there are currently no pharmacological treatments approved [4]

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SURMOUNT-5 was a 72-week, open-label, Phase 3b randomised trial of 751 adults with obesity but without diabetes, comparing maximum-tolerated tirzepatide (10 or 15 mg) against maximum-tolerated semaglutide (1.7 or 2.4 mg)