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Soucy F and Grgoire M: Efficacy of prednisone for severe refractory ulcerative interstitial cystitis

The glucagon component directly tells the liver to burn its stored fat, which is why the gap is so large

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This phenomenon occurs because weight loss, particularly when substantial and occurring over a relatively short period, can mobilise uric acid from tissues and temporarily elevate serum uric acid levels, potentially triggering acute gout episodes in those predisposed to the condition