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It will produce 8-oxo-guanines and promote action of OGG1 to generate AP sites

Manufactured in a UK Laboratory Produced Under Strict Quality Control Standards

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The shRNA sequence (TRCN0000322995) targeting ATG10 was designed according to MISSION shRNA Plasmid DNA (MERCK) and synthesized and joined the FastDigest BshTI/FastDigest EcoRI linearized (Thermo Fisher) pLKO.1-GST DAF vector with T4 DNA ligase (EL0011, Thermo Fisher)

Serious adverse events are rare with proper medical oversight