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These features include a shortened effective atrial refractory period, delayed atrial conduction, and increased reentrant excitation, all of which are closely associated with alterations in atrial structure and function ( 2.3 Signaling mechanisms in atrial cardiomyopathy The development of ACM is closely related to the electrophysiological activity of the atria, particularly the atrial remodeling process

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The cardiovascular effects of retatrutide are multidimensional, and several of them are strongly protective