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The FDA nod, which the companies announced on Friday, is specifically for the reduction of risk of sustained decline in estimated glomerular filtration rate (eGFR), end-stage kidney disease and cardiovascular death and hospitalization in adults with CKD at risk of progression

Research institutions benefit from this guarantee structure as it provides flexibility for experimental planning and budget management

The main limitation is that reduced GSH is vulnerable to stomach acid and digestive enzymes, which break it down before absorption

Major teaching hospitals will experience no change

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