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Healthcare providers should engage in shared decision-making with patients, discussing the substantial metabolic benefits of tirzepatide alongside the theoretical thyroid risks, to determine whether the medication is appropriate for each individual's clinical situation and risk profile

*Correspondence: Jia Li, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Mendelian Randomization Pleiotropy RESidual Sum and Outlier (MR-PRESSO) analysis was conducted to detect outlier instrument ( is sufficient (1.00) assuming the true causal OR of carnitine on COVID-19 is 0.8, given the involved sample size and the significance level as 0.05 ( Results We analyzed the role of carnitine on COVID-19 using the two-sample MR approach

These experimental results were compared with the predicted values from the fitted model