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Nevertheless, significant increases in DAMPs (including IL-33 and HMGB1) were observed in bronchoalveolar lavage fluids, with IL-33 promoting M2 polarization and HMGB1 inducing M1 polarization through the advanced glycation end-products receptor pathway

What followed was about a year of deep research, listening to David Schmidt, reading everything I could find, and eventually working closely with many clients on their own patch journeys

In this video, @lisa_jewell_md_plasticsurgery explains that treatment is highly individualized

This is particularly helpful after orthopedic or soft tissue surgery

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