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Glycolysis-derived intermediates in EC dysfunction and atherosclerosis Lactate, derived from glycolysis and glutamine catabolism, functions as a crucial carbon source for cellular metabolism and a key signaling molecule [42]

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To decipher the role of the circadian clock in renal metabolism, we studied diurnal changes in renal metabolic pathways using integrated transcriptomic, proteomic, and metabolomic analysis performed on control mice and mice with an inducible deletion of the circadian clock regulator Bmal1 in the renal tubule (cKOt)