The pivotal Phase 2 trial a 48-week study published in The New England Journal of Medicine in 2023 produced these results in adults with obesity (and no diabetes), at the highest dose of 12 mg weekly: Average weight loss of around 24% from baseline A clear dose-response, with even the 4 mg dose producing roughly 17% weight loss Continued weight loss right up to the 48-week endpoint, with no plateau in sight For context, similar Phase 2 data for Wegovy showed around 15% weight loss at 68 weeks
"I think we've got tighter regulation here, which we always have had," he said
No Prescription Required (Illegal) This is the single most important red flag, and it's absolute: if a company or website will sell you semaglutide, tirzepatide, or any other GLP-1 medication without a prescription from a licensed healthcare provider, they're operating illegally
Metabolism Changes During GLP-1 Treatment Your basal metabolic rate (BMR) naturally decreases as you lose weight, a phenomenon called adaptive thermogenesis
Customizable & Versatile: The device allows clinics to tailor treatments to clients specific needs, whether they need skin tightening, muscle toning, or fat reduction
