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A study proved that p53 could bind to dipeptidyl-peptidase 4 (DPP4) to reduce the DPP4-dependent oxidization of PUFAs to inhibit ferroptosis in colorectal cancer cells[46]

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Astrocytes release ATP through both vesicular and non-vesicular routes, with subsequent conversion to adenosine by ectonucleotidases [322326]

The problem is, the first phase generates a burst of free radicals that can damage liver tissue if not quickly balanced by antioxidants

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