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One well-documented interaction is with certain anti-epileptic drugs: high-dose pyridoxine may reduce the plasma levels of phenytoin and phenobarbital by enhancing their hepatic metabolism, potentially diminishing their anticonvulsant efficacy
Beyond survival, patients on N+I maintained better health-related quality of life (HRQoL), with a lower risk of deterioration and fewer side effects impacting daily life
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Pharmacokinetics and tolerability of semaglutide in subjects with hepatic impairment
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