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The most commonly reported side effects are mild and transient: injection site redness or minor bruising, transient fatigue in the first one to two weeks, and occasionally mild headache following the first few injections, a pattern sometimes attributed to the acute shift in cellular energy metabolism as AMPK pathways are upregulated [3]

Opportunities exist to develop drugs with a durable weight-loss effect in the absence of ongoing pharmacotherapy which would be greatly attractive to patients

Early Phase (Days 1-7) Anti-inflammatory effects may manifest within the first 1-3 days as the peptide begins modulating inflammatory mediators

Rasmussen, S., Corya, B