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In addition to its antioxidant properties, glutathione is one of the best detoxification agents

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108 Alterations in dietary composition impact not only the availability of nutrients within tumor cells but also the surrounding microenvironment, thereby offering potential opportunities to impede tumor growth 109 (Table 1)

Therefore, leveraging the activity of E2 metabolites may potentially be an effective therapeutic strategy for reduction of fibrosis in MASLD