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Progress towards therapies for disease modification in Parkinsons disease

These effects are generally dose-dependent and vary by which statin is used, with simvastatin at higher doses carrying more muscle risk than rosuvastatin or pravastatin

SOC refers to the highest level of classification in medical terminology, used to organize and categorize medical information based on human systems or organs ( Data analysis We employed disproportionality methods, including the Reporting Odds Ratio (ROR), Proportional Reporting Ratio (PRR), Bayesian Confidence Propagation Neural Network (BCPNN), and Multi-Item Gamma Poisson Shrinker (MGPS) methods to detect signal strength (Table 1)

- Then, in ATTAIN-MAINTAIN, those same individuals were randomized for another 52 weeks to once daily orforglipron vs placebo, on top of lifestyle support

Sikiric P, Seiwerth S, Rucman R, Turkovic B, Stancic Rokotov D, Brcic L, et al