These pleiotropic actions suggest that GLP-1RAs could become valuable tools in the integrative management of patients with AITD, particularly those who also struggle with obesity, insulin resistance, or metabolic dysfunction
Wargo et al., 2009
On the other hand, a lower dosage has shown the ability to slow down melanogenesis, without the addition of the blood clot
Additionally, ER stress can induce AMPK activation via increased cytosolic Ca 2+ levels, providing an alternative route for autophagy initiation (Hyer-Hansen et al., 2007)
"You just try to hit it from the top and hit from the bottom, and that's when you end up getting in trouble: At some point, it's gonna come out, and you don't have lot choice as to when it does," Adams said