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The activation of ERK1/2 may be partly responsible for the elevated iNOS and COX-2 expression level induced by LPS in RAW 264.7 cells [41]
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Scharf, Tingjun Hou, Tianhua Zhou, Ming-Wei Wang, Yan Zhang URL: Published: Cell Research, 25 August 2021, volume 31, pages 11631175 This study reports four high-resolution structures of full-length melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein stimulated by different ligands, including the FDA-approved drug bremelanotide (Vyleesi)
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