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J Clin Invest 2014;124:4473-88.ArticlePubMedPMC 58

Pre-Treatment Risk Stratification: Who Faces Higher Complications Individual risk for GI complications depends on age, NSAID duration, Helicobacter pylori status, prior ulcer history, and concurrent corticosteroid use

However, weight loss itself increases the risk of gallbladder disease, so its hard to be sure that its the semaglutide thats causing the issue

Statements from Novo Nordisk emphasize the overall safety profile of semaglutide while acknowledging the need for ongoing monitoring of vision-related side effects

The multiple roles of life stress in metabolic disorders