Once glutathione neutralizes a free radical, it becomes oxidized (GSSG), meaning it is temporarily "spent." For it to become useful again, it must be recycled back into its reduced state
3-AR is specific to adipose tissue (unlike 1 and 2, which are in the heart and lungs)
Preclinical safety data In mouse studies, 5-amino-1mq was well-tolerated even at doses several times higher than those producing metabolic effects
Pathogens 14(8):780 Guz NR, Stermitz FR, Johnson JB, Beeson TD, Willen S, Hsiang JF, Lewis K (2001) Flavonolignan and flavone inhibitors of a Staphylococcus aureus multidrug resistance pump: structure activity relationships
Seminal plasma and spermatozoa have several antioxidant enzymes -glutathione peroxidase, glutathione reductase, superoxide dismutase