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Similar content being viewed by others Introduction Colorectal cancer (CRC) is the second leading cause of cancer-related mortality, and the incidence of early-onset colon cancer has been increasing worldwide globally in recent years 1

A clinical test also found that combining pharmacological ascorbate with platinum-based chemotherapy helped with tumor shrinkage in patients with advanced non-small cell lung cancer

Figures were prepared using UCSF Chimera version 1.15 or ChimeraX 1.4 68,69

The binding leads to stimulation of endothelial cells and triggers pathways such as MAPK/ERK, PI3K/Akt, and PLC signaling to drive proliferation, migration, and tube formation

Journal of orthopaedic research : official publication of the Orthopaedic Research Society , 21 (6), 976-83