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HGF and c-met inhibitors in anticancer therapy The c-Met is not only a marker linked to metastatic properties but is also a suitable drug target and the molecules which inhibit HGF/c-Met signaling are expected to serve for therapeutic intervention [51]

For instance, because of its role in DNA repair, it is essential for cell division and plays a significant role in the formation and repair of all cells

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While murine models suggest atrial GLP-1R expression, the precise cardiac cell types expressing GLP-1R, especially in humans, are yet to be conclusively identified [33]

The clinical significance of anti-exenatide antibody formation is unknown at this time