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Of the participants, 60% (n = 120) were treated with tirzepatide and 40% (n = 80) with semaglutide

While further research has to be conducted to solidify the link between cognition and IGF-1, IGF-1 has been proven to act at AMPARs to initiate changes in synaptic structure and protein expression

9 To counteract this, you must prioritise protein and resistance exercise

While these treatments can be effective in promoting weight loss, it's important to be aware of the potential side effects and to discuss your options with your doctor

As of mid-2026 it is not approved as a standalone drug for obesity, type 2 diabetes, or any other indication by the FDA, the EMA, or comparable regulators