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found that in the mouse mode heme oxygenase 1 (HMOX-1), heat induced and regulated by early growth response factor 1 (EGR1), can mediate ferroptosis in KCs and cause liver injury [47]

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This is the stage where people often say things like: I dont feel obsessed with food anymore or I was able to eat just one cookie and feel satisfied without having to go back for more. And for someone who has spent years battling cravings and hunger, this shift can feel almost miraculous