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Semaglutide has been shown to reduce CV risk in people with T2D and established or high risk of CV disease
Notably, although gallbladder disorders frequently manifest, advanced gastrointestinal complications such as intestinal obstruction and periprocedural aspiration, and emergent concerns regarding suicidality and ocular problems require further longitudinal studies to refine the usage guidelines for GLP-1 RAs in susceptible populations
The drug is reportedly effective for weight loss because it mimics hormones that regulate appetite and blood sugar (GLP-1 and GIP)
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