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The authors note that the current publication represents an early proof-of-concept analysis and that larger, longer-term studies will be needed to confirm the durability of the reproductive benefits observed

Orlistat relies on reducing the calories absorbed from dietary fat, making it most effective when combined with a low-fat diet

Seek urgent medical advice if you develop severe or persistent abdominal pain , especially if accompanied by nausea, vomiting, or fever

Medicines and Healthcare Products Regulatory Agency (2022)

Avoid or limit alcohol consumption , as it can affect blood glucose levels, impair judgment regarding food choices, add empty calories, and potentially worsen gastrointestinal side effects