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Among the available therapeutic options, surgical laser therapy has been reported to be well tolerated by patients [40] and effective in the management of physiological gingival pigmentation, smokers melanosis, and pigmentation associated with LaugierHunziker syndrome

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Broccoli sprouts contain vastly higher concentrations of the necessary compounds, and standardization ensures a consistent, clinically relevant dose of sulforaphane to effectively trigger the Nrf2 signaling pathway without requiring the consumption of massive quantities of cruciferous vegetables, which can be difficult for patients with gastrointestinal sensitivities to digest

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Identification and characterization of the functional amino acids at the active center of pig liver thioltransferase by site-directed mutagenesis