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J Biol Chem 279: 25832592

Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimers disease

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Furthermore, studies have demonstrated that elevated AMPK expression can modulate downstream protein expression, resulting in reduced levels of sterol regulatory element-binding protein (SREBP), which subsequently decreases fatty acid synthase (FAS) expression and suppresses lipogenesis 37