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Elevated systemic oxidative stress can lead to notable fibrinogen oxidation and structural alterations, which are associated with impaired fibrin polymerization and enhanced resistance to plasmin-induced lysis

De Felice M, Renard J, Hudson R, Szkudlarek HJ, Pereira BJ, Schmid S, et al

Chromatographic analysis of the ethyl acetate fraction of avocado leaf extract identified 11 compounds, with 11-tetradecyn-1-ol acetate, 8-hexadecenal, 14-methyl-(Z)-, and cyclopropane carboxaldehyde being the most abundant, likely contributing to the fraction's anti-HTN effects (463)